When UCSF Can Serve as IRB of Record

Federally funded studies at grant stage

As part of the new common rule and the NIH single IRB mandate, all domestic multi-site research studies are required to use a single IRB. You will need to consult with the UCSF IRB to determine which institution should serve as the IRB of Record before submitting your proposal. Please fill out this form as soon as possible and email it to [email protected]. You will be contacted for a consultation.
 

You will be asked to schedule a call to discuss your study. You will be emailed after the call with all information needed for your grant application or instructions on how to pursue using other IRBs as the reviewing IRB.

Examples of the most common federal funders: NIH (all institutes), DoD, DoJ, AHRQ, CDC, etc.

All other studies

If you would like UCSF to act as the IRB of Record for a site in your study, please fill out this Request Form.
 

We ask that you fill out this form prior to submitting your initial review/modification to the UCSF IRB whenever possible to prevent inefficiencies in the IRB process.

Further instructions will be provided after IRB receipt of the Request Form.

Considerations for serving as the IRB of record

When agreeing to serve as the IRB record, UCSF will review the study for all sites that are engaged in research. UCSF generally does not provide IRB review for sites that do not meet the federal engagement criteria, even when the site’s local policies are more restrictive than federal requirements.

The UCSF IRB uses IREx to coordinate with external sites. Relying sites will be asked to obtain an IREx account.

All relying sites must obtain any and all applicable local ancillary committee approvals (for example, Radiation Safety Committee). The UCSF IRB will not conduct the IRB review for sites that cannot secure ancillary committee reviews. The UCSF HRPP is unable to facilitate any such reviews

Resources

  • Reliance Request Form - This form is used when a study team would like to request that a collaborating site(s) use the UCSF IRB as its IRB of Record. 

 

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