The Human Research Protection Program (HRPP) reviews and monitors research involving human subjects at UCSF and several affiliate institutions to ensure the welfare, safety, privacy, and ethical treatment of participants in human research studies. Read more about the HRPP program.
The HRPP is comprised of 3 groups:
- Institutional Review Board (IRB), which reviews human subject research studies — learn how to submit to the IRB.
- Quality Improvement Unit (QIU), which conducts monitoring, education and other QI activities.
- Human Gamete, Embryo and Stem Cell Research (GESCR) Committee.
Grant or Contract Termination Notices
What steps should I take with the IRB if I receive a grant or contract termination notice for a study involving participants?
Once a Termination notice is received:
- Submit a protocol violation/incident reporting form and select "loss of resources" (see Post Approval Reporting Form), even if you will be filing an appeal.
- Report the change in study status, and, if applicable, describe the measures you are taking to ensure a safe tapering or termination of study procedures for participants.
- Include the agency termination notice and a projected timeline for closing the study.
Note:
- The IRB will advise if a study modification will be necessary.
- Once study enrollment, visits, record review, and data analysis are completed, promptly submit a Study Closeout report.
- Do not submit a study closeout report if an appeal is currently pending. Ensure that the study does not expire by submitting Continuing Review Reports according to schedule.
If you need assistance completing the reporting form, please submit an Ask Andy request, and an analyst will contact you.
Priority Review for Research on the Health Impact of Changes in Federal Policies since January 2025 and Dobbs Impact Research
The HRPP has appointed a Rapid Review Team (RRT) to ensure Research on the Health Impact of Changes in Federal Policies since January 2025 and Dobbs Initiative Related Research is fast tracked to approval. See instructions on how to request rapid review for studies falling under these categories.
